We have a wide range of products in different strengths and formulations. The products fall under the following categories:
Antibiotics, Antifungals, Antimalarials, Anti-allergy, Anti-ulcer, Antacids, Pain killers, Nutritional supplements, Surgical disposables and Laboratory reagents.
Amoxicillin 1g, Clarithromycin 500 mg, Esomeprazole 20 mg.
First Line Treatment Regimen for eradication of Helicobacter pylori infection and prevention of duodenal
ulceration due to H. pylori
Administer (Amoxicillin 1g, Clarithromycin 500 mg, Esomeprazole 20 mg) BD for 14 days
ESOMEPRAZOLE 20MG TABLETS
Name of the medicinal product:Â
Esomeprazole 20mg Tablets
Qualitative and quantitative composition:
Each enteric coated tablet contains Esomeprazole Trihydrate BP equivalent to Esomeprazole 20mg.
Therapeutic indications
Adults: Esomeprazole 20mg tablets are indicated in adults for:
- Gastro-oesophageal Reflux Disease (GORD)
- treatment of erosive reflux oesophagitis
- long-term management of patients with healed oesophagitis to prevent relapse – symptomatic treatment of gastro-oesophageal reflux disease (GORD) In combination with appropriate antibacterial therapeutic regimens for the eradication of Helicobacter pylori and
- healing of Helicobacter pylori associated duodenal ulcer and
- prevention of relapse of peptic ulcers in patients with Helicobacter pylori associated ulcers Patients requiring continued NSAID therapy
- healing of gastric ulcers associated with NSAID therapy.
- prevention of gastric and duodenal ulcers associated with NSAID therapy, in patients at risk. Treatment of Zollinger Ellison Syndrome Esomeprazole 20mg tablets are indicated in adolescents from the age of 12 years for: Gastro-oesophageal Reflux Disease (GORD)
- treatment of erosive reflux oesophagitis
- long-term management of patients with healed oesophagitis to prevent relapse – symptomatic treatment of gastro-oesophageal reflux disease (GORD) In combination with antibiotics in treatment of duodenal ulcer caused by Helicobacter pylori.
Name of the medicinal product :
Pepgel Plus Suspension Qualitative and quantitative composition: The active components of Pepgel Plus are:- Simethicone 25mg/5ml
- Magnesium Hydroxide 200mg/5ml
- Dried Aluminium Hydroxide Gel 225mg/5ml
- Also contains sorbitol.
Pharmaceutical form:
Oral suspension White suspension, homogenous after shaking.Therapeutic indications:
The symptomatic relief of:- Dyspepsia.
- Heartburn.
- Flatulence.
- Hyperacidity
Posology and method of administration For oral administration:
Adults : 5-10ml taken 20 minutes to 1 hour after meals and at bedtime or as required. Children: As an appropriate proportion of the adult dose. Children under 5 years: Maximum of 5ml t.d.s. Elderly The normal adult dose is appropriate.Contraindications:
Should not be used in patients who are hypersensitive to any of the active substances or excipients, are severely debilitated or suffering from kidney failure, or hypophosphataemia.Name of the medicinal product:
Cefuroxime 500 mg TabletsQualitative and quantitative composition:
Each tablet contains cefuroxime axetil which is equivalent to 500 mg cefuroxime.Therapeutic indications:
Cefuroxime axetil is indicated for the treatment of the infections listed below in adults and children from the age of 3 months .- Acute streptococcal tonsillitis and pharyngitis.
- Acute bacterial sinusitis.
- Acute otitis media.
- Acute exacerbations of chronic bronchitis.
- Cystitis – Pyelonephritis.
- Uncomplicated skin and soft tissue infections.
- Treatment of early Lyme disease.
- Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Posology and method of administration:
Posology: The usual course of therapy is seven days (may range from five to ten days).AMOXICILLIN TRIHYDRATE EQUIVALENT TO 875 MG AMOXICILLIN AND POTASSIUM CLAVULANATE EQUIVALENT TO 125 MG OF CLAVULANIC ACID TABLETS
Name of the medicinal product:
Levofloxacin 500mg Film-coated TabletsQualitative and quantitative composition:
Each film-coated tablet contains Levofloxacin Hemihydrate USP equivalent to anhydrous levofloxacin 500mg.Therapeutic indications:
Levofloxacin 500mg Film-coated Tablets is indicated in adults for the treatment of the following infections:- Acute bacterial sinusitis
- Acute exacerbations of chronic bronchitis
- Community-acquired pneumonia
- Complicated skin and soft tissue infections For the above-mentioned infections Levofloxacin 500mg Film-coated Tablets should be used only when it is considered inappropriate to use antibacterial agents that are commonly recommended for the initial treatment of these infections.
- Pyelonephritis and complicated urinary tract infections.
- Chronic bacterial prostatitis
- Uncomplicated cystitis
- Inhalation Anthrax: post exposure prophylaxis and curative treatment
- Levofloxacin 500mg Film-coated Tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin. Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Posology and method of administration:
Levofloxacin 500mg Film-coated Tablets are administered once or twice daily. The dosage depends on the type and severity of the infection and the susceptibility of the presumed causative pathogen. Levofloxacin 500mg Film-coated Tablets may also be used to complete a course of therapy in patients who have shown improvement during initial treatment with intravenous levofloxacin; given the bioequivalence of the parenteral and oral forms, the same dosage can be used.Name of the medicinal product:
Clarithromycin 500mg Film-coated Tablets Qualitative and quantitative composition: Each tablet contains Clarithromycin 500 mg. Colour: Titanium DioxideTherapeutic indications
Consideration should be given to official guidance on the appropriate use of antibacterial agents. Clarithromycin tablets are indicated in adults and children 12 years and older. Clarithromycin Tablets are indicated for treatment of the following infections caused by susceptible organisms Indication include:- Lower respiratory tract infections for example: acute and chronic bronchitis, and pneumonia.
- Upper respiratory tract infections for example: sinusitis and pharyngitis.
- Clarithromycin is appropriate for initial therapy in community acquired respiratory infections and has been shown to be active in vitro against common and atypical respiratory pathogens as listed in the microbiology section.
- Clarithromycin is also indicated in skin and soft tissue infections of mild to moderate severity.
- Clarithromycin in the presence of acid suppression effected by omeprazole or lansoprazole is also indicated for the eradication of H. pylori in patients with duodenal ulcers. Clarithromycin is usually active against the following organisms in vitro:
- Gram-positive Bacteria: Staphylococcus aureus (methicillin susceptible); Streptococcus pyogenes (Group A beta-hemolytic streptococci); alpha-hemolytic streptococci (viridans group); Streptococcus (Diplococcus) pneumoniae; Streptococcus agalactiae; Listeria monocytogenes.
- Gram-negative Bacteria: Haemophilus influenzae; Haemophilus parainfluenzae; Moraxella (Branhamella) catarrhalis; Neisseria gonorrhoeae; Legionella pneumophila; Bordetella pertussis; Helicobacter pylori; Campylobacter jejuni.
- Mycoplasma: Mycoplasma pneumoniae; Ureaplasma urealyticum.
- Other Organisms: Chlamydia trachomatis; Mycobacterium avium; Mycobacterium leprae
- Anaerobes: Macrolide-susceptible Bacteroides fragilis; Clostridium perfringens; Peptococcus species; Peptostreptococcus species; Propionibacterium acnes.
- Clarithromycin has bactericidal activity against several bacterial strains. The organisms include Haemophilus influenzae; Streptococcus pneumoniae; Streptococcus pyogenes; Streptococcus agalactiae; Moraxella (Branhamella) catarrhalis; Neisseria gonorrhoeae; H. pylori and Campylobacter spp.
Name of the medicinal product:
Cefixime Tablets 400mgQualitative and quantitative composition:
Each tablet contains Cefixime (as Trihydrate) USP equivalent to Anhydrous Cefixime 400mgTherapeutic indications:
Cefixime is an orally active cephalosporin antibiotic which has marked in vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms. It is indicated for the treatment of the following acute infections when caused by susceptible micro-organisms:- Upper Respiratory Tract Infections (URTI): e.g. otitis media; and other URTI where the causative organism is known or suspected to be resistant to other commonly used antibiotics, or where treatment failure may carry significant risk.
- Lower Respiratory Tract Infection: e.g. bronchitis.
- Urinary Tract Infections: e.g. cystitis, cystourethritis, uncomplicated pyelonephritis. Clinical efficacy has been demonstrated in infections caused by commonly occurring pathogens including Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Kliebsiella species, Haemophilus influenzae (beta-lactamase positive and negative), Branhamella catarrhalis (beta-lactamase positive and negative) and Enterobacter species. Cefixime is highly stable in the presence of beta-lactamase enzymes. Most strains of enterococci (Streptococcus faecalis, group D Streptococci) and Staphylococci (including coagulase positive and negative strains and methicillin-resistant strains) are resistant to Cefixime. In addition, most strains of Pseudomonas, Bacteriodes fragalis, Listeria monocytogenes and Clostridia are resistant to Cefixime.
Name of the medicinal product:
Azithromycin 500 mg Film-coated TabletsQualitative and quantitative composition:
Azithromycin 500 mg Film-coated Tablets: Each film-coated tablet contains azithromycin dehydrate USP equivalent to azithromycin 500 mg.Pharmaceutical form:
Film-coated tablet. White, oblong shaped, film coated tablets with a score line on one side and plain on the other side.Therapeutic indications:
For treatment of the following infections, when caused by microorganisms sensitive to azithromycin :- Acute bacterial sinusitis (adequately diagnosed)
- Acute bacterial otitis media (adequately diagnosed)
- Pharyngitis, tonsillitis
- Acute exacerbation of chronic bronchitis (adequately diagnosed)
- Mild to moderately severe community acquired pneumonia
- Infections of the skin and soft tissues of mild to moderate severity e.g. folliculitis, cellulitis, erysipelas.
- Uncomplicated Chlamydia trachomatis urethritis and cervicitis Consideration should be given to official guidance on the appropriate use of antibacterial agents.
Composition
Ketoconazole ..2% w/v Zinc Pyrithione…………1% w/v In Aloe Vera gel base…10% w/vPharmaceutical Form.
Light blue coloured viscous liquidTherapeutic Indications
V – Druf is indicated for the prevention and treatment of infections in which the yeast Malassezia (previously called Pityrosporum) is likely to be involved, such as dandruff, seborrhoeic dermatitis and tinea (pityriasis) versicolor.Posology and Method of Administration
- For topical administration.
- Adults, Elderly and Children:
- Wash affected areas and leave for 3-5 minutes before rinsing.
Contraindications Known hypersensitivity to ketoconazole, zinc pyrithione or any of the excipients.
TERBINAFINE HYDROCHLORIDE 1% CREAM
- In onychomycoses, Griseofuvin has done its part for so many years but relapse rates, high incidence of liver toxicity and limited spectrum of antifungal activity make terbinafine, Oncosil, the preferred treatment of choice. A continuous administration regimen of 250 mg, 6 weeks for fingernail and 12 weeks for toenail onychomycosis has a 76% mycological and clinical cure rate higher than itraconazole.
- According to a meta-analysis by Gupta and Foley et al (2015), Oncosil 1% cream is considered first line in treatment of Pityariasis versicolor on a twice daily dosing with a 90% mycological cure rate on day 14 and 100% complete cure rate on the 28th day. Topical Oncosil, for Pityriasis versicolor can be administered with the first line systemic antifungal, itraconazole (Itranox) 200 mg for 7 days to boost cure rates and treat stubborn tinea versicolor with a mycological cure of 90% (Kose et al, 2002) and a complete cure rate of 87% (Galimberti et al, 1987).
- In tinea corporis and pedis, a period of 4 weeks of 250 mg/day PO in single dose or divided every 12 hours will achieve cure rates and Oncosil is first line.â€
- In onychomycoses, Griseofuvin has done its part for so many years but relapse rates, high incidence of liver toxicity and limited spectrum of antifungal activity make terbinafine, Oncosil, the preferred treatment of choice. A continuous administration regimen of 250 mg, 6 weeks for fingernail and 12 weeks for toenail onychomycosis has a 76% mycological and clinical cure rate higher than itraconazole.
- According to a meta-analysis by Gupta and Foley et al (2015), Oncosil 1% cream is considered first line in treatment of Pityariasis versicolor on a twice daily dosing with a 90% mycological cure rate on day 14 and 100% complete cure rate on the 28th day. Topical Oncosil, for Pityriasis versicolor can be administered with the first line systemic antifungal, itraconazole (Itranox) 200 mg for 7 days to boost cure rates and treat stubborn tinea versicolor with a mycological cure of 90% (Kose et al, 2002) and a complete cure rate of 87% (Galimberti et al, 1987).
- In tinea corporis and pedis, a period of 4 weeks of 250 mg/day PO in single dose or divided every 12 hours will achieve cure rates and Oncosil is first line.â€
Qualitative and quantitative composition
- Each hard gelatin capsule contains Itraconazole 100mg BP as pellets
Therapeutic indications
- Vulvovaginal candidiasis,
- Oral candidiasis
- Dermatophytoses caused by organisms susceptible to itraconazole (Trichophyton spp., Microsporum spp., Epidermophyton floccosum) e.g. tinea pedis, tinea cruris, tinea corporis, tinea manuum,
- Pityriasis versicolor,
- Onychomycoses caused by dermatophytes and/or yeasts,
- Systemic candidiasis,
- Cryptococcal infections (including cryptococcal meningitis). In immunosuppressed patients suffering from cryptococcosis and in patients with cryptococcosis of the CNS Itraconazole is indicated only if the usually recommended initial therapy seems to be inappropriate or ineffective
- Histoplasmosis.
- Aspergillosis. Itraconazole can be used to treat patients suffering from invasive aspergillosis who were found to be refractory or intolerant to Amphotericin B
- Maintenance therapy in AIDS patients to prevent relapse of underlying fungal infection who were found to be refractory or intolerant to first-line systemic anti-fungal therapy is inappropriate or has proved ineffective. Due to PK properties, orally administered itraconazole (capsules) should not be used as the initial treatment in patients with severe life-threatening forms of systemic mycoses. Oral forms should be used as a continuation therapy, after initial treatment with i.v. itraconazole. Consideration should be given to official guidance regarding the appropriate use of antifungal agents.
Fluconazole is indicated in adults for the prophylaxis of:
- Relapse of cryptococcal meningitis in patients with high risk of recurrence.
- Relapse of oropharyngeal or esophageal candidiasis in patients infected with HIV who are at high risk of experiencing relapse.
- To reduce the incidence of recurrent vaginal candidiasis (4 or more episodes a year).
- Prophylaxis of candida infections in patients with prolonged neutropenia (such as patients with hematological malignancies receiving chemotherapy or patients receiving Hematopoietic Stem Cell Transplantation.
Dosage and Administration Posology
The dose should be based on the nature and severity of the fungal infection. Treatment of infections requiring multiple dosing should be continued until clinical parameters or laboratory tests indicate that active fungal infection has subsided. An inadequate period of treatment may lead to recurrence of active infection.Fluconazole is indicated in adults for the prophylaxis of:
- Relapse of cryptococcal meningitis in patients with high risk of recurrence.
- Relapse of oropharyngeal or esophageal candidiasis in patients infected with HIV who are at high risk of experiencing relapse.
- To reduce the incidence of recurrent vaginal candidiasis (4 or more episodes a year).
- Prophylaxis of candida infections in patients with prolonged neutropenia (such as patients with hematological malignancies receiving chemotherapy or patients receiving Hematopoietic Stem Cell Transplantation.
Dosage and Administration Posology
The dose should be based on the nature and severity of the fungal infection. Treatment of infections requiring multiple dosing should be continued until clinical parameters or laboratory tests indicate that active fungal infection has subsided. An inadequate period of treatment may lead to recurrence of active infection.ARTESUNATE 100MG; MEFLOQUINE HYDROCHLORIDE BP (EQUIVALENT TO MEFLOQUINE BASE 200MG) TABLETS
Name of the medicinal product:
Duo-Artepep 320 mg/40 mg film-coated tablets.Qualitative and quantitative composition:
Each film-coated tablet contains 320 mg piperaquine tetraphosphate (as the tetrahydrate; PQP) and 40 mg Dihydroartemesinin.Therapeutic indications:
Duo-Artepep is indicated for the treatment of uncomplicated Plasmodium falciparum malaria in adults, adolescents, children and infants 6 months and over and weighing 5 kg or more. Consideration should be given to official guidance on the appropriate use of antimalarial medicinal products.Posology and method of administration:
Posology: Duo-Artepep should be administered over three consecutive days for a total of three doses taken at the same time each day.DIHYDROARTEMESININ 80MG, PIPERAQUINE PHOSPHATE 640MG FOR ORAL SUSPENSION
Name of the medicinal product:
Corither AB InjectionComposition:
Artemether 150mg/2mlDescription:
Arteether is an ethyl ether derivative of artemisinin, which is a natural product of the medicinal plant Artemisia annua. It is used as a second line drug in severe cases of malaria.Pharmacology
Pharmacodynamics Alpha-Beta Arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage. α-β Arteether is concentrated in parasitized erythrocytes and interacts with haeme in the parasite by virtue of its endoperoxide bridge. Iron mediated cleavage of the bridge releases a highly reactive free radicals species that binds to membrane proteins, which leads to lipid peroxidation, damage to endoplasmic reticulum and inhibits protein synthesis, which results in lysis of the malarial parasite Pharmacokinetics Alpha-Beta Arteether (IM) is quickly absorbed from the injection site reaching therapeutic levels within the first hour. It is metabolised in the liver to the de-ethylated derivative dihydroartemisinin. It has an elimination half-life of ~ 24 hr and is more stable than the other artemisinin compounds.Indications:
- Arteether is an anti-malarial used for the treatment of severe falciparum malaria active against P. falciparum strains that are resistant to chloroquine, mefloquine, halofantrine, quinine, pyrimethamine, cycloguanil and amodiaquine.
- Alpha/beta arteether is also used for the treatment of uncomplicated falciparum malaria.
Dosage and Administration:
Alpha/beta Arteether in Adults: Intramuscular injection of one ampoule, containing 150mg / arteether, daily for 3 consecutive days (i.e. total dose 450 mg irrespective of body weight or 3mg/kg/day for a 50kg adult). Child dose: Intramuscular injection of 3mg / arteether/kg body weight daily for 3 consecutive days.Contraindications
Alpha-Beta Arteether injection is contraindicated in patients hypersensitive to artemisinin derivatives,Name of the medicinal product:
Co-Corither DS 80 mg/480 mg tabletsQualitative and quantitative composition:
One tablet contains 80 mg artemether and 480 mg lumefantrine.Therapeutic indications:
Co-Corither DS is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria in adults, children and infants of 5 kg and above. Consideration should be given to official guidance regarding the appropriate use of antimalarial agents.Posology and method of administration:
Posology Adults and children weighing 35 kg and above or more than 12 years of age One tablet of 80 mg/480 mg at the time of initial diagnosis, again 1 tablet after 8 hours and then 1 tablet twice daily (morning and evening) on each of the following two days (total course comprises 6 tablets of 80 mg/480 mg).Treatment and stand-by emergency treatment:
The treatment should be administered at the time of initial diagnosis or at onset of symptoms. Method of administration Tablets for oral administration. To increase absorption, Co-Corither DS should be taken with food or a milky drink. If patients are unable to tolerate food, Co-Corither DS should be administered with water, but the systemic exposure may be reduced. Patients who vomit within 1 hour of taking the medication should repeat the dose.Name of the medicinal product:
Corflex Forte TabletsQualitative and quantitative composition:
Each film coated tablet contains: – Glucosamine Sulfate Potassium Chloride USP 500 mg – Chondroitin Sulfate Sodium USP 200 mg – Methylsulfonylmethane USP 200 mg – Ascorbic Acid (Vitamin C) BP 50 mg – Manganese Sulphate BP 20 mg – all-rac-Alpha-Tocopheryl Acetate (Vitamin E) BP 12.5 mgTherapeutic Indications:
Corflex Forte provides efficacious quantities of glucosamine sulfate, chondroitin sulfate and methylsulfonylmethane, combined with vitamin C, vitamin E and manganese for optimizing joint health. It is indicated for the treatment of:- Osteoarthritis and rheumatoid arthritis.
- Pain relief in osteoarthritis
- Rehabilitation of damaged cartilage
Dosage and Directions for Use:
One tablet to be taken twice a day.Contraindications
Hypersensitivity to the active ingredients or to any of the excipients.Qualitative and quantitative composition
Each tablet contains Diclofenac Potassium 50mg Chlorzoxazone USP 250mg and Paracetamol BP 325mg.Therapeutic Indications:
Flamacor MR is indicated for:- Soft tissue injuries with spasms and inflammation \
- Neck, shoulder and back pain
- Menstrual pain
- Tendonitis
- Tenosynovitis
- Bursitis
- Muscle pain
- Relief of the pain of osteoarthritis of knees and hands
- Headache
- Ear Pain
PARACETAMOL BP 450MG, CAFFEINE BP 50MG, CODEINE PHOSPHATE BP 10MG, DOXYLAMINE SUCCINATE USP 5MG TABLETS
CHLORZOXAZONE 300MG
Qualitative and quantitative composition
Each tablet contains Chlorzoxazone USP 250mg and Paracetamol BP 325mg.
Therapeutic Indications:
Myocor is indicated for the relief of severe skeletal spasm and pain associated with medical problems such as:
- Sprains and strains
- Myalgia
- Tension headaches
- Traumatic muscle injuries
- Low back pain
- Fibrositis
- Cervical root and disc syndromes
Contraindications
Hypersensitivity to the chlorzoxazone and paracetamol or to any of the excipients.